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目的了解人类免疫缺陷病毒(HIV)感染妇女所生婴儿的神经心理发育情况,为制定该特殊群体儿童健康改善措施提供依据。方法选取2010年7月-2013年11月期间昆明市HIV感染妇女所生的1岁婴儿为研究对象,按条件配对,利用BayleyⅢ婴幼儿发育量表对婴儿进行神经心理发育测评,问卷收集有关信息。结果暴露组婴儿除了语言量表外,认知、运动、社会情绪、适应性行为量表得分(分别是94.09、96.27、79.60和86.09)均明显低于非暴露组的得分(101.36、98.52、93.86和92.89,P<0.01),暴露组婴儿社会情绪、适应性行为量表得分低于边缘及以下水平的比例(45.45%和38.64%),显著高于非暴露组婴儿(22.73%和15.91%)。结论 HIV感染对婴儿神经心理发育影响明显,应加强对HIV感染妇女所生婴儿神经心理发育的保健指导工作。
Objective To understand the neuropsychological development of infants born to women infected with human immunodeficiency virus (HIV) and provide evidence for the improvement of children’s health in this special group. Methods One-year-old infants born from HIV-infected women in Kunming from July 2010 to November 2013 were selected as the research objects. According to the conditional pairing, the neurological development of infants was assessed by using Bayley Ⅲ Infant Development Scale. The questionnaires were collected to collect relevant information . Results In the exposed group, scores of cognitive, motor, social emotion and adaptive behavior scale (94.09, 96.27, 79.60 and 86.09 respectively) were significantly lower than those of non-exposed group (101.36,98.52,93.86 And 92.89, P <0.01). The scores of social emotion and adaptive behavior scale of infants in exposed group were lower than the marginal and sub-proportions (45.45% and 38.64%), significantly higher than that of non-exposed infants (22.73% and 15.91% . Conclusion HIV infection has significant effect on the neuropsychological development of infants. It is necessary to strengthen the guidance on the neuropsychological development of infants born to HIV-infected women.