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目的:探讨中西医结合治疗2型糖尿病患者临床疗效观察及其安全性。方法:70例2型糖尿病患者根据随机分组法随机分为治疗组(n=36)和对照组(n=34)。治疗组采用中西医结合治疗,对照组仅给予西药治疗。两组总疗程均为3个月。对比分析两组疗程结束后治疗总有效率,治疗前后Hb A1c、FPG、2h PG、TC、TG、血浆黏度、血糖达标时间及不良反应情况。结果:治疗组总有效率高于对照组(P<0.05);两组Hb A1c、FPG以及2 h PG治疗后均较治疗前显著下降(P<0.05);治疗组Hb A1c、FPG以及2h PG治疗后显著低于对照组(P<0.05);治疗组TC、TG以及血浆黏度治疗后均较治疗前显著下降(P<0.05),而对照组TC、TG以及血浆黏度治疗后与治疗前比较无统计学差异(P>0.05);治疗组TC、TG以及血浆黏度治疗后显著低于对照组(P<0.05);治疗组血糖达标时间显著快于对照组(P<0.05);治疗期间两组均未见明显不良反应。结论:中西医结合治疗2型糖尿病患者临床疗效显著,安全可靠,具有重要研究价值。
Objective: To investigate the clinical efficacy and safety of traditional Chinese and western medicine in the treatment of type 2 diabetes mellitus. Methods: Seventy patients with type 2 diabetes were randomly divided into treatment group (n = 36) and control group (n = 34) according to the randomization method. Treatment group with Integrative Medicine treatment, control group only given Western medicine treatment. The two groups were treated for 3 months. The total effective rate after treatment was compared between the two groups. Hb A1c, FPG, 2h PG, TC, TG, plasma viscosity, blood glucose compliance time and adverse reactions before and after treatment were compared. Results: The total effective rate of the treatment group was higher than that of the control group (P <0.05). The levels of Hb A1c, FPG and 2h PG in the two groups were significantly lower than those before treatment (P <0.05) The levels of TC, TG and plasma viscosity in the treatment group were significantly lower than those before treatment (P <0.05), while those in the control group were lower than those in the control group (P <0.05) (P <0.05). The TC, TG and plasma viscosity of the treatment group were significantly lower than those of the control group after treatment (P <0.05); the treatment group had significantly higher blood glucose level than the control group (P <0.05) No obvious adverse reactions were found in the group. Conclusion: The clinical curative effect of type 2 diabetes mellitus patients with integrated traditional Chinese and western medicine is safe, reliable and has important research value.