目的:研究脑脊液置换联合鞘内注射对蛛网膜下腔出血(SAH)的治疗作用。方法:将127例SAH患者随机分为试验组和对照组;对照组应用镇静、止痛、药物(EACA、尼莫地平)等常规治疗方法,试验组在常规治疗的基础上,应用腰穿脑脊液置换和鞘内注射地塞米松。结果:SAH的头痛症状以及脑积水、蛛网膜粘连、脑血管痉挛等主要并发症的症状的发生率、死亡率,试验组明显少于对照组,经统计学处理,有显著差异。结论:脑脊液置换联合鞘内注射治疗蛛网膜下腔出血,可明显降低SAH主要并发症的发生率和死亡率,其方法简便,效果可靠,有非常实用的临床价值。 Objective: To study the therapeutic effect of cerebrospinal fluid replacement combined with intrathecal injection on subarachnoid hemorrhage (SAH). Methods: A total of 127 patients with SAH were randomly divided into experimental group and control group. The control group was treated with conventional therapy such as sedation, analgesia and drugs (EACA, nimodipine). Based on routine treatment, And intrathecal dexamethasone. Results: The incidence of headache and the incidence of major complications such as hydrocephalus, arachnoid adhesion and cerebral vasospasm in SAH were significantly lower than those in the control group. There were significant differences between the two groups in terms of statistics. Conclusion: Cerebrospinal fluid replacement combined with intrathecal injection of subarachnoid hemorrhage can significantly reduce the incidence of major complications and mortality of SAH. The method is simple, reliable and has very practical clinical value.