论文部分内容阅读
AFT最早是从患暴发性、急性疾病的多种动物中分离出的,而这些动物的肝脏普遍都有损害。关于肝癌发病率与AFT的日摄入量的相关已有详细报导。广泛的流行病学研究证明,人对其急性毒性和致癌性是敏感的。但是作为人类疾病的因素还只是根据表面现象推测出的证据。为此,本文就AFT作用模式的某些实验进行了讨论,可能提出一些关于人对AFT敏感性的直接证据。AFT的致癌性已为人们所熟知,然而应该重提的是以低至0.015 ppm的AFT连续或在
AFT was first isolated from a variety of animals suffering from fulminant, acute illness, and the liver of these animals generally have damage. The correlation between the incidence of liver cancer and the daily intake of AFT has been reported in detail. Extensive epidemiological studies have shown that people are sensitive to their acute toxicity and carcinogenicity. But as a human disease factor is only based on speculation on the surface of the evidence. For this reason, some of the experiments on AFT mode of action are discussed in this paper, and some direct evidence of human sensitivity to AFT may be presented. The carcinogenicity of AFTs is well known, however, it should be recalled that AFTs as low as 0.015 ppm continuously or at