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目的:评估~(14)C-尿素呼气试验(~(14)C-UBT)对幽门螺杆菌(HP)感染的诊断价值。方法:对200例1月内未曾使用可能影响HP检测结果的药物者同步完成快速尿酶试验(RUT)、病理、~(14)C-UBT检测,以病理(HE染色)、RUT均阳性为诊断HP感染的标准,评价~(14)C-UBT对HP感染的诊断价值。结果:~(14)C-UBT的敏感性89.7％,特异性98.4％,阳性预测值98.4％,准确性93.4％,阴性预测值88.1％。结论:~(14)C-UBT是HP感染无创伤、敏感而特异的诊断方法。
Objective: To evaluate the diagnostic value of ~ (14) C-urea breath test (~ (14) C-UBT) on Helicobacter pylori (HP) infection. Methods: Rapid urease test (RUT), pathology and ~ (14) C-UBT were performed in 200 patients who did not use HP test results within 1 month. Pathological (HE staining) and RUT were positive The diagnosis of HP infection criteria, evaluation of ~ (14) C-UBT diagnosis of HP infection. Results: The sensitivity of ~ (14) C-UBT was 89.7%, the specificity was 98.4%, the positive predictive value was 98.4%, the accuracy was 93.4%, and the negative predictive value was 88.1%. Conclusion: ~ (14) C-UBT is a noninvasive, sensitive and specific diagnostic method for HP infection.