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目的:对住院病人病历抗菌药物利用和费用进行分析,以提高该类药物应用合理性。方法:随机抽查1997年第1次住院病历1000份并查阅药库1997年药品使用目录,采用DDD分析方法和药物经济学方法,分析合理用药、用药频度和药物费用。结果:应用的抗菌药物主要为头孢菌素类、喹诺酮类和青霉素类;不合理用药病历占抗菌药物病历总数的20%;在全部抗菌药物病历中,头孢菌素类药物占30.9%,DDDs排序前10位中有3种,并且该类药物支出占购药金额的40%以上。结论:头孢菌素类药物应用欠合理,喹诺酮类剂量偏大,其它药物基本合理.
OBJECTIVE: To analyze the utilization and cost of medical records of inpatients in order to improve the rationality of such drugs. Methods: Randomly examining the first inpatient medical record of 1000 in 1997 and checking the catalog of drug use in 1997, using DDD analysis method and pharmacoeconomics method to analyze the rational drug use, frequency of drug use and drug cost. Results: The main antimicrobial agents were cephalosporins, quinolones and penicillins. The irrational use of medical records accounted for 20% of the total number of antimicrobial medical records. Of all the antimicrobial medical records, cephalosporins accounted for 30.9% There are 3 of the top 10 DDDs in the ranking, and these drugs account for more than 40% of the purchase price. Conclusion: The application of cephalosporins is not rational, quinolone dosage is too large, other drugs are reasonable.