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目的:分析肺炎支原体(MP)抗体阳性患儿的临床和实验室资料,为诊断和治疗肺炎支原体感染提供依据。方法:采用富士明胶颗粒凝集法,检测具有发热或呼吸道症状5～7天住院患儿的血清MP混合抗体,对其中807例MP抗体阳性患儿的临床资料进行分析。结果:5 405例患儿中MP抗体阳性率14.9%,2008～2010年MP抗体阳性率之间差异有统计学意义(P<0.05);女患儿MP抗体阳性率高于男患儿,差异有统计学意义(P<0.05);学龄前组MP感染率最高(P<0.05);2008年MP感染率没有明显的季节差异,2009年秋季MP感染率最高,2010年夏秋季节MP感染率高于春冬季节;807例MP抗体阳性患儿发生肺外合并症129例,占16.0%。结论:MP感染的好发人群有提前趋势,且在儿童中的感染呈逐年上升趋势;MP感染的季节性每年均有变化,MP感染肺外合并症多见。
Objective: To analyze the clinical and laboratory data of Mycoplasma pneumoniae (MP) antibody-positive children and provide basis for diagnosis and treatment of Mycoplasma pneumoniae infection. Methods: Fuji gelatin particle agglutination method was used to detect serum MP mixed antibody in hospitalized children with fever or respiratory symptoms 5-7 days, and the clinical data of 807 MP-positive children were analyzed. Results: The positive rate of MP antibody in 5 405 cases was 14.9%. The positive rate of MP antibody in 2008-2010 was statistically significant (P <0.05). The positive rate of MP antibody in female children was higher than that in male children (P <0.05). The prevalence of MP infection in preschool children was the highest (P <0.05). There was no obvious seasonal difference in MP infection rate in 2008, but the MP infection rate was the highest in autumn of 2009 and the MP infection rate in summer and autumn of 2010 was high In the spring and winter seasons, there were 129 cases of extrapulmonary complications in 807 MP-positive children, accounting for 16.0%. CONCLUSIONS: The prevalence of MP infection is on the rise and the prevalence of infection in children is increasing year by year. The seasonal variation of MP infection varies from year to year. MP infection is more common in extrapulmonary patients.