壶腹周围肿瘤是指包括胰头、胆总管下端、壶腹部及十二指肠乳头的肿瘤。其中绝大多数为恶性肿瘤,只有极少数病例为良性疾患,如胆管绒毛膜瘤、胰管乳头状瘤、十二指肠腺瘤等。壶腹周围肿瘤的早期症状常不典型,进展到中晚期多为肿瘤压迫胰管及其共同开口处,从而表现为无痛性渐近性黄疸和/或不明原因腰背部固性胀痛等,更甚者可导致急性胰腺炎或者急性化脓性胆管炎。此时的手术切除率较低,治疗效果欠佳,所以壶腹 The periampullary tumor refers to a tumor including the pancreatic head, the lower common bile duct, the ampulla, and the duodenal papilla. The vast majority of them are malignant tumors. Only a few cases are benign disorders such as cholangiomas, pancreatic duct papillomas, duodenal adenomas, and the like. The early symptoms of the periampullary tumor are often not typical, and most of the tumor progresses to the late stage of the tumor, which is the pancreatic duct and its common opening. This manifests itself as painless asymptotic jaundice and/or unexplained lumbar dorsal solid pain. More may lead to acute pancreatitis or acute suppurative cholangitis. At this time, the resection rate is low and the treatment effect is not good, so the ampulla is