婴幼儿血管瘤(IH)是婴幼儿最常见的肿瘤。血管瘤干细胞(HemSC)是一种来源于胚胎间充质的CD133+细胞。HemSC注入裸鼠体内后,可以分化为内皮细胞和周细胞/平滑肌细胞,形成血管网。整合蛋白α6亚族已被证明与恶性胶质瘤干细胞的致瘤作用,血管生成及内皮、间充质祖细胞有关。该文旨在对整合蛋白α6在HemSC中的作用进行研究。记 Infantile hemangiomas (IH) are the most common tumors in infants and young children. Hemagglutinin stem cell (HemSC) is a CD133 + cell derived from embryonic mesenchyme. HemSC injected into nude mice, can differentiate into endothelial cells and pericytes / smooth muscle cells, the formation of vascular network. The α6 subfamily of integrins has been shown to be involved in tumorigenicity, angiogenesis, and endothelial and mesenchymal progenitor cells of glioblastoma stem cells. The aim of this paper is to investigate the role of integrin α6 in HemSC. Remember