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丹参酮系指从丹参 Salvia miltiorrhiza Bge.根提出的酯溶性成分总丹参酮。总丹参酮包括10个单体,其中隐丹参酮,二氢丹参酮Ⅰ、羟基丹参酮、丹参酮Ⅱ_(B)和丹参酸甲酯在体外对金黄色葡萄球菌有明显抑制作用,对溶血性链球菌也有一定抑制作用。局部应用总丹参酮对巴豆油引起的小鼠实验性炎症具有明显的抗炎作用;灌胃给药对伤寒、副伤寒甲、乙三联菌苗致热的家兔有降低体温作用。本文综合报告北京市工农兵医院等13个单位应用丹参酮治疗各种化脓性感染的疗效。所用片剂,每片含总丹参酮不少于79毫克,隐丹参酮不少于19毫克,成人每日12～14片,分3～4次服;油膏为总丹参酮中隐丹参酮含量在10%以上的2%油膏,供外用。
Tanshinone refers to the ester-soluble constituent total tanshinone proposed from Salvia miltiorrhiza Bge. Total tanshinones include 10 monomers, among which cryptotanshinone, dihydrotanshinone I, hydroxytanshinone, tanshinone II_(B), and methyl salvianic acid have significant inhibitory effects on Staphylococcus aureus in vitro, and also have certain inhibition on hemolytic streptococci. effect. The topical application of total tanshinones has significant anti-inflammatory effects on experimental inflammation in mice induced by croton oil; intragastric administration has a hypothermic effect on rabbits with fever caused by typhoid, paratyphoid fever A and B. This article comprehensively reports the efficacy of tanshinone in the treatment of various purulent infections in 13 units such as Beijing Gongnong Bing Hospital. The tablets used contain not less than 79 mg of total tanshinone and not less than 19 mg of cryptotanshinone, 12 to 14 tablets per day for adults and 3 to 4 servings. The ointment contains 10% of total tanshinones in total tanshinones. The above 2% ointment is for external use.