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目的:探讨口腔修复膜在手术治疗OLP中的应用及疗效。方法:选择OLP患者80例,随机分为两组,治疗组采取手术切除病变+口腔修复膜植入术,对照组口服羟氯喹治疗,随访3月~3年,平均随访1年。结果:2组病例总有效率比较,差异有统计学意义,手术治疗组明显优于对照组(x2=22.6,P﹤0.05)。结论:手术治疗OLP虽然可能引起口腔黏膜新的创伤,但其能在更短的时间、最大限度地治愈OLP,效果明显。而且口腔修复膜的使用可以最大程度地避免术后疤痕的形成,解除患者心理负担。手术切除OLP并结合口腔修复膜修复创面可作为OLP的一种可供选择的治疗方法。
Objective: To investigate the application and efficacy of oral repair membrane in the surgical treatment of OLP. Methods: Eighty OLP patients were randomly divided into two groups. The treatment group was treated with surgical resection of the lesion and oral repair membrane. The control group was treated with hydroxychloroquine. The patients were followed up for 3 months to 3 years and followed up for an average of 1 year. Results: The total effective rate of two groups was statistically significant, the surgical treatment group was significantly better than the control group (x2 = 22.6, P <0.05). Conclusion: Although OLP may cause new trauma to oral mucosa, OLP can cure OLP to the maximum extent in a shorter time. And the use of oral repair membrane can prevent the formation of postoperative scar, relieve the patient’s psychological burden. Surgical removal of OLP combined with oral repair of wound repair wounds can be used as an alternative treatment of OLP.