根尖周病是口腔科一种常见的感染性疾病,近年来研究表明,尖周感染是以厌氧菌为主体的混合感染,其中产黑色素类杆菌在混合感染中占据中心位置。Iwu亦从根尖肉芽肿的厌氧培养中证实厌氧菌的存在,并与临床上的叩痛与自发痛有关。说明产黑色类杆菌属及其碎片、分解产物和内毒素等可能是根尖肉芽肿的活跃或向急性期过渡的重要致病菌,甲硝唑因其抗厌氧菌而被用作控制口腔感染。对 Apical periodontal disease is a common infectious disease in stomatology. In recent years, studies have shown that periapical infection is a mixed infection mainly consisting of anaerobic bacteria, and the melanobacteria that produce it occupy the center of the mixed infection. Iwu also confirmed the presence of anaerobic bacteria in anaerobic cultures of apical granulomas and was associated with clinically painful and spontaneous pain. Description of production of black genus Bacillus and its fragments, decomposition products and endotoxins may be active or acute transitional period of apical granuloma of the important pathogenic bacteria, metronidazole because of its anti-anaerobic bacteria were used to control oral infections. Correct