NK细胞是T细胞抗原受体阴性(CD_3~-即α~- ,β~-,γ~(-δ-))大颗粒淋巴细胞。他们通常表达某些细胞表面标志,如人的CD_(10)和NKH-1(Leu-19)以及小鼠的NK1.1/NK2.1。他们介导细胞溶解反应不需要靶组胞上MHCI类分子或MHCⅡ类分子的表达。某些α~(β+)或γ~δT淋巴细胞可能表达类似NK细胞活性的细胞溶解作用,特别是在激 NK cells are T cell antigen receptor negative (CD_3 ~ - namely α ~ -, β ~ -, γ ~ (-δ-)) large granular lymphocytes. They usually express certain cell surface markers such as human CD_ (10) and NKH-1 (Leu-19) and mouse NK1.1 / NK2.1. They do not require the expression of MHC class I molecules or MHC class II molecules in the target cell as they mediate the cytolytic response. Some α ~ (β +) or γ ~ δT lymphocytes may express cytolysis similar to NK cell activity, particularly in the