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胆石性胰腺炎是指因胆石症而引起的急性胰腺炎,约占急性胰腺炎的40～60%,我国的急性胰腺炎亦多系胆石症所致.胆石性胰腺炎无论在发病机理、自然病程、诊断和治疗等方面均与酒精性胰腺炎有所不同.近年来,许多学者对此症作了较深入的研究,现根据有关国外文献对胆石性胰腺炎作如下综述.发病机理关于胆石性胰腺炎的发病机理,至今尚未完全阐明.1901年,Opie根据1例因急性坏死性胰腺炎而死亡者的尸体解剖中,发现有一枚结石嵌顿于Vater壶腹,提出了急性胰腺炎的“共同通道学说”.他认为结石嵌顿阻塞了胆汁与胰液的共同通道,使胆汁返流入胰管激活胰酶,导致了急性胰腺炎的发生.但是,“共同通
Gallstone pancreatitis is caused by cholelithiasis caused by acute pancreatitis, accounting for about 40 to 60% of acute pancreatitis, acute pancreatitis in our country are also more caused by cholelithiasis. Gallstone pancreatitis both in the pathogenesis, nature Course of disease, diagnosis and treatment are all different from alcoholic pancreatitis .In recent years, many scholars made a more in-depth study of this disease, are based on the relevant literature on gallstone pancreatitis made the following review. Pathogenesis on gallstones The pathogenesis of pancreatitis has not been fully elucidated until now. In 1901, Opie found a stone embedded in the ampulla of Vater, based on the autopsy of a patient who died of acute necrotizing pancreatitis, proposing acute pancreatitis ”Common Channel Doctrine. " He believes that stone incarceration block the common channel of bile and pancreatic juice, bile reflux into the pancreatic duct activation pancreatin, leading to the occurrence of acute pancreatitis.