论文部分内容阅读
类癌是有恶性倾向常见的肠道内分泌肿瘤,当出现肝转移时可产生特征性的症状.作者研究瑞典中心地区的103例恶性类癌(1978～1986),86例为手术发现,其余作肝穿刺活检,所有病人组织学证实为类癌.病人入院后作常规检查,甲状腺功能并测定:胰多肽(PP),绒膜促性腺激素α,β(HCGα、β),降钙素,胃泌素,血浆神经多肽K(NPK),尿5羟吲哚乙酸(5-HIAA),尿皮质醇,和CT,B超等检查.肿瘤标本作H、E染色显示细胞结构及内分泌肿瘤的生长特征,进一步用Grimelius, Masson, Sevier-Munger银染证实.病人平均年龄59岁,男女比为46∶57,其中原发肿瘤在回肠75例,空肠4例,盲肠3例,阑尾2例,
Carcinoids are common endocrine tumours with malignant tendencies. They produce characteristic symptoms when liver metastases occur. The authors studied 103 cases of malignant carcinoid tumors in the center of Sweden (1978-1986). 86 cases were found by surgery, others were Liver biopsy, all patients histologically confirmed as carcinoid. Patients were admitted to the hospital for routine examination, thyroid function and determination: pancreatic polypeptide (PP), chorionic gonadotropin α, β (HCGα, β), calcitonin, stomach Cortisol, plasma neuropeptide K (NPK), urinary 5-hydroxyguanidine acetic acid (5-HIAA), urinary cortisol, and CT, B-ultrasonic examination. Tumor specimens for H, E staining showed cell structure and endocrine tumor growth Characteristics, further confirmed by Grimelius, Masson, Sevier-Munger silver staining. The average age of the patients was 59 years, male to female ratio was 46:57, of which the primary tumor was in the ileum 75 cases, jejunum 4 cases, cecum in 3 cases, appendix in 2 cases,