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目的:比较阿立哌唑与氯氮平用于治疗女性精神分裂症患者的护理质量评定及疗效和安全性。方法:选取2012年3月—2014年3月间收治的女性精神分裂症患者90例,依据治疗方法的不同将其分为观察组患者与对照组患者,每组45例;观察组患者均给予阿立哌唑治疗,对照组患者均给予氯氮平治疗;比较两组患者治疗后护理质量评定、疗效和安全性。结果:观察组患者治疗护理后的个人卫生、社会兴趣以及社会能力的评分值均明显优于对照组患者(P<0.05);其不良反应的发生率显著低于对照组(P<0.05)。结论:阿立哌唑与氯氮平用于治疗女性精神分裂症患者,其疗效阿立哌唑优于氯氮平,且安全性更强。
OBJECTIVE: To compare the quality of care and the efficacy and safety of aripiprazole and clozapine in the treatment of female schizophrenia. Methods: Ninety female schizophrenia patients who were admitted to our hospital from March 2012 to March 2014 were divided into observation group and control group according to the different treatment methods, with 45 cases in each group. Patients in observation group were given Aripiprazole treatment, the control group were given clozapine treatment; comparison of two groups of patients after treatment quality assessment, efficacy and safety. Results: The scores of personal hygiene, social interest and social ability in observation group were significantly better than those in control group (P <0.05). The incidence of adverse reactions in observation group was significantly lower than that in control group (P <0.05). CONCLUSIONS: Aripiprazole and clozapine are more effective than clozapine in the treatment of female schizophrenia, and their safety is better.