曼陀罗种子主要含莨菪烷型生物碱——莨菪碱(1)、东莨菪碱(2)及其类似物。研究了在种子发芽过程中这两种化合物的经时变化。当种子用水浸湿后,(1)和(2)的含量立即开始降低,在发芽后第4天才检测出这些生物碱。在此期间,培养基中(1)和(2)均检测不出,表明这些生物碱以某种方式参与和子叶生长有关的代谢。这两种生物碱大部分存在于种子的胚乳和营养层 Datura seeds contain mainly tropane alkaloids - scopolamine (1), scopolamine (2) and its analogues. The time-course changes of these two compounds during seed germination were studied. After the seeds were soaked in water, the contents of (1) and (2) immediately began to decrease, and the alkaloids were detected only on the fourth day after germination. During this time, neither media nor (1) and (2) were detectable in the medium, suggesting that some of these alkaloids are involved in cotyledon-related metabolism. Most of these two alkaloids exist in the endosperm and trophic layers of the seed