目的：探讨利维爱和钙尔奇Ｄ合用对预防和治疗绝经后骨质疏松的疗效并观察体重指数的变化及阴道流血情况等。方法：２７例绝经后的妇女，口服利维爱１２５ｍｇ，每天１次和钙尔奇Ｄ６００ｍｇ，每天２次，用Ｈｏｌｏｇｉｃ双能Ｘ线骨密度仪测量骨密度。结果：治疗１２个月后腰椎正侧位的骨密度分别较治疗前增加１４３％和２１５％（Ｐ＜００１）。结论：证明利维爱和钙尔奇Ｄ合用可以增加中国绝经后妇女的骨密度。 OBJECTIVE: To investigate the efficacy of combined use of Levi and Calcium D in the prevention and treatment of postmenopausal osteoporosis and to observe the changes of body mass index and vaginal bleeding. METHODS: Twenty-seven postmenopausal women received oral Levi 1  25 mg once daily and Calcium  D 600 mg twice daily, using a Hologic dual-energy X-ray absorptiometry to measure bone mineral density. Results: At 12 months after treatment, the BMD of lumbar spine was increased by 143% and 215% respectively (P <001). CONCLUSIONS: It has been demonstrated that the combination of Levi and Calc-D increases bone mineral density in postmenopausal women in China.