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研究了苦皮藤素 对粘虫 (Mythimna separata)和小地老虎 (Agrotis ypsilon)幼虫的选择毒性机理。结果表明 ,对照组小地老虎幼虫血液、中肠和整体匀浆的酯酶活性显著高于粘虫幼虫。经苦皮藤素 注射或胃毒处理后 ,粘虫幼虫酯酶活性均受到显著抑制而降低 ,血液和中肠酯酶同工酶谱主带减弱 ;而小地老虎幼虫血液酯酶活性显著升高 ,血液酯酶同工酶谱主带加强。因此认为 ,酯酶活性和酯酶同工酶的差异是苦皮藤素 对粘虫和小地老虎幼虫选择毒性的机制之一。
The selective toxicity mechanism of celangulin against the larvae of Mythimna separata and Agrotis ypsilon was studied. The results showed that the esterase activity of blood, midgut and whole homogenate of the control group was significantly higher than that of armyworm larvae. After injection of celangulin or stomach poisoning, the esterase activity of armyworm larvae was significantly inhibited and decreased, while the main band of esterase isozyme in the blood and midgut decreased. However, the esterase activity of larvae of Landrace was significantly increased High, blood esterase isoenzyme spectrum with the main strengthening. Therefore, it is considered that the difference between esterase activity and esterase isozyme is one of the mechanisms by which cephalosporin selects toxicity to armyworm and small tiger larvae.