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目的:观察中药组方和氟伐他汀对代谢综合征(MS)高血脂患者血脂水平的影响。方法:选择MS高血脂患者80例,随机分为甲组40例,用中药组方治疗;乙组40例用氟伐他汀治疗,观察12周。检测各组血糖(FPG)、胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白(HDL-C)、低密度脂蛋白(LDL-C)、体重、腰围、体质数(BMI)。结果:与治疗前比较,治疗后两组血脂、血糖、体重、腰围、BMI等水平均较治疗前明显降低(P<0.05)。治疗后,两组间各指标比较,体重、腰围、BMI、TG、LDL-C等差异显著(P<0.05)。结论:中药组方和氟伐他汀均能明显降低伴MS高血脂患者的血脂水平,中药组方还能降低患者体重。
Objective: To observe the effects of traditional Chinese medicine and fluvastatin on blood lipid levels in hyperlipidemic patients with metabolic syndrome (MS). Methods: Eighty patients with MS hyperlipidemia were randomly divided into 40 cases of group A and treated with traditional Chinese medicine. 40 cases of group B were treated with fluvastatin for 12 weeks. The levels of blood glucose (FPG), cholesterol (TC), triglyceride (TG), high density lipoprotein (HDL-C), low density lipoprotein (LDL-C), body weight, waist circumference and body mass index (BMI) Results: The levels of blood lipids, blood glucose, body weight, waist circumference and BMI in the two groups after treatment were significantly lower than those before treatment (P <0.05). After treatment, there was significant difference in body weight, waist circumference, BMI, TG, LDL-C among the two groups (P <0.05). Conclusion: Both traditional Chinese medicine and fluvastatin can significantly reduce the level of serum lipids in patients with hyperlipidemia, and the traditional Chinese medicine group can reduce body weight.