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急性病毒性肝炎演变为暴发型肝衰竭的发病机制迄今还未完全阐明。由于通过电镜检查可直接发现免疫复合物,因此某些作者认为,严重的肝脏损害可能是由于免疫复合物沉积于肝窦所引起。由于过去尚未见到暴发型病毒性肝炎或药物性肝衰竭时对循环免疫复合物的研究,本文作者在这方面进行了观察。
The pathogenesis of acute viral hepatitis evolving into fulminant hepatic failure has not yet been fully elucidated. Because of the direct observation of immune complexes by electron microscopy, some authors suggest that severe liver damage may be caused by the deposition of immune complexes in the sinusoids. The authors of this article have looked at circulating immune complexes in the past when they have not seen any episodes of fulminant viral hepatitis or drug-induced liver failure.