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目的：评估幽门螺杆菌细胞毒抗体（ＣａｇＡＨＰ－ＩｇＧ）检测在消化道疾病诊断中的应用价值。方法：对胃镜检查、组织学、尿素酶试验证实的１５７例各种消化道疾病患者的血清，用酶免疫检测试剂盒进行ＣａｇＡＨＰ－ＩｇＧ抗体的检测。结果：在４５例消化道溃疡病人血清中ＣａｇＡＨＰ－ＩｇＧ抗体阳性３７例，阳性率８２．２％，９９例消化道炎症病人血清中ＣａｇＡＨＰ－ＩｇＧ抗体阳性３４例，阳性率３４．３％，１３例胃癌病人血清中ＣａｇＡＨＰ－ＩｇＧ抗体阳性８例，阳性率６２％。结论：ＣａｇＡＨＰ－ＩｇＧ的检测在临床诊断胃与十二指肠非侵入性检测中可用于幽门螺杆菌分型试验，是检测Ⅰ型幽门螺杆菌感染的可信指标。
Objective: To evaluate the value of CagAHP-IgG detection in the diagnosis of digestive diseases. Methods: Serum samples of 157 patients with various gastrointestinal diseases confirmed by gastroscopy, histology and urease test were detected by enzyme immunoassay kit for CagAHP-IgG antibody. Results: The positive rate of CagAHP-IgG in serum of 45 patients with peptic ulcer was 37 (82.2%). The positive rate of CagAHP-IgG in 34 patients with gastrointestinal inflammation was 34.3% Cases of gastric cancer patients CagAHP-IgG antibody positive in 8 cases, the positive rate of 62%. Conclusion: The detection of CagAHP-IgG can be used in the typing test of Helicobacter pylori in clinical diagnosis of gastric and duodenal noninvasive detection and is a credible indicator for detecting type I H. pylori infection.