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目的探讨肝硬变患者胸水的发生率及其相关因素。方法分析 40 2例肝硬变患者胸水的发生与性别、民族、年龄、肝硬变病因、腹水、门、脾静脉内径、肝功能 Child-pugh分级以及肝功能生化指标之间的关系。结果肝硬变患者胸水的发生率男显著高于女 ( P<0 .0 5 ) ;腹水组显著高于无腹水组 ( P<0 .0 1) ;肝功能 B级和 C级组显著高于肝功能 A级组 ( P<0 .0 5 ,P<0 .0 1) ;而在不同的民族、年龄、肝硬变病因、腹水量以及门、脾静脉内径之间均无显著性差异。肝硬变胸水组血清白蛋白显著低于非胸水组 ( P<0 .0 1) ,而血清总胆红素在两组之间无显著性差异。结论肝硬变患者胸水的发生与性别、有无腹水、肝功能损害程度以及低白蛋白血症等因素密切相关 ,而与民族、年龄、肝硬变病因、腹水量、血清总胆红素水平以及门、脾静脉内径无明显关系。
Objective To investigate the incidence of pleural effusion in cirrhotic patients and its related factors. Methods The relationship between the occurrence of pleural effusion and the gender, ethnicity, age, cause of liver cirrhosis, ascites, portal vein, splenic vein diameter, Child-pugh classification of liver function and biochemical indexes of liver function were analyzed in 402 cirrhotic patients. Results The incidence of pleural effusion in cirrhotic patients was significantly higher than that in women (P <0.05), that in ascites group was significantly higher than that in ascites group (P <0.01), and that in B and C group was significantly higher (P <0.05, P <0.01), but there was no significant difference in different ethnic groups, age, etiology of liver cirrhosis, ascites volume and the diameter of portal vein and splenic vein . Serum albumin in cirrhotic pleural effusion group was significantly lower than that in non-pleural effusion group (P <0.01), while serum total bilirubin had no significant difference between the two groups. Conclusions The occurrence of pleural effusion in patients with cirrhosis is closely related to gender, presence of ascites, degree of hepatic impairment, and hypoalbuminemia, but not related to ethnicity, age, cause of cirrhosis, amount of ascites, total serum bilirubin As well as the diameter of the spleen vein, no significant relationship.