随着年事逐渐增高,许多脏器功能也逐渐减退.肾脏是老龄导致功能减退最易受损的器官之一.随衰老发生的肾脏改变表现为明显的结构和肾功能改变(肾血流减少、肾小球滤过率减少和肾小管重吸收的减退).由于老年人易罹患诸如动脉硬化、高血压、糖尿病等疾病,接触毒物和药物的机会多,进一步增加了发生肾脏病的危险性. As age becomes progressively higher, many organ functions diminish gradually, and the kidneys are one of the most susceptible organs for aging to cause hypofunction, and the changes in the kidneys with aging are marked by structural and renal changes (decreased renal blood flow , Decreased glomerular filtration rate and diminished renal tubular reabsorption.) As the elderly are at risk of diseases such as arteriosclerosis, hypertension and diabetes, there is a greater chance of exposure to poisons and drugs, further increasing the risk of developing kidney disease .