漂白粉等氯制剂在水处理中作为消毒剂已经有相当长的历史,而二氧化氯(ClO~2)作为一种新兴的取代氯制剂的消毒剂,已经被证明具有用量少、消毒效果好、毒性小、使用后无有害残留物质和病原菌不会产生耐药性等优点,在欧、美的一些发达国家,ClO~2已经取代漂白粉被用作饮用水的消毒剂。但是,获取ClO~2的途径很多,即制备ClO~2有多种方法,以往的毒性试验大多是采用的化学发生法制备的纯ClO~2进行的。对于近年来使用较多的稳定性粉状ClO~2的毒理作用,尚未见有详细的研究报道。本研究探讨了用含有不同浓度稳定性粉状ClO~2的去氯自来水作为小白鼠的饮用水,在56天的饲养过程中,对小白鼠的体重增长、饵料利用率和肝(肾)脏/体重比值进行了测定,并且对小白鼠内部器官 Chlorine bleach and other chlorine preparations have a long history as a disinfectant in water treatment, and chlorine dioxide (ClO 2), as a new disinfectant for replacing chlorine preparations, has been shown to have low dosage and good sterilizing effect , Small toxicity, no harmful residual substances after use and pathogenic bacteria will not produce drug resistance, etc. In some developed countries in Europe and the United States, ClO ~ 2 has replaced bleach powder as a disinfectant for drinking water. However, there are many ways to obtain ClO ~ 2, that is, there are a variety of methods for preparing ClO ~ 2. Most of the previous toxicity tests were performed using pure ClO ~ 2 prepared by chemical method. For the toxic effects of the more stable powdery ClO ~ 2 used in recent years, no detailed studies have been reported yet. This study explored the use of dechlorinated tap water containing different concentrations of powdered stabilized ClO ~ 2 as drinking water for mice. During the 56-day feeding period, body weight gain, feed utilization and liver (kidney) / Body weight ratio was measured, and the internal organs of mice