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乙胺碘呋酮(简称“乙碘”),用于治疗心律失常已20年,开始以广谱、高效、副作用少的特征,很快被临床选用,但随应用的日益广泛,其毒副作用渐多,某些反应还十分严重,甚至难以预测;文献尚有致死报道,重要原因之一是日量多、疗程长。我们用口服“乙碘”常规量洽疗心律失常,观察142例,发现毒副反应并不甚严重。本文通过对其发生率、反应类型、可能机制、影响因素及停药指征的研讨,为合理用药和减少毒副反应发生提供参考。
Amiodarone (referred to as “iodine”), for the treatment of arrhythmia has been 20 years, beginning with a broad spectrum, high efficiency, less side effects of the characteristics of clinical application soon, but with the increasingly widespread application of its toxic side effects Increasingly, some of the reactions are still very serious and even unpredictable. There are still some reports of death in the literature. One of the important reasons is that the daily dose is large and the course of treatment is long. We use oral “B iodine” conventional amount of cardioversion arrhythmia, observed 142 cases, found that toxicity is not serious. This article through its incidence, types of reactions, possible mechanisms, influencing factors and drug withdrawal indications for the rational use of drugs and reduce the incidence of side effects provide a reference.