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目的研究同一个体，不同预矫度对准分子激光屈光性角膜切削术治疗近视疗效的影响。方法双 眼近视度相差≥一２．００Ｄ的 １３６例（２７２眼）近视患者，分为低屈光度组（Ⅰ 组）和高屈光度组（Ⅱ 组），对．ＰＲＫ术后 随访１年的裸眼视力、残余屈光度及角膜ｈａｚｅ等作统计学分析。结果ＰＲＫ术后１年，Ⅰ组及Ⅱ组的裸眼视力分 别为 ０． ６９±０． ３３和 ０． ６２±０． ３８，组间差异无统计学意义（ Ｐ ＞０．０５）；残余近视度在预矫度±０． ５０Ｄ和±１． ００Ｄ以 内者，Ⅰ组为 ７６眼（５５． ８８％）和 ９５眼（６９． ８５％），Ⅱ组为 ４５眼（３３． ０９％）和 ７２眼（５２． ９４％），组间差异极显著（ Ｐ ＜ ０．０１）；±２．００Ｄ以内者，Ⅰ组为９８眼（７２．２２％），Ⅱ组为８７眼（６３．９７％），组间差异无显著性（Ｐ＞０．０５）；角膜 ｈａｚｅ在随访的 １、３、６及 １２个月中，组间均无显著差异（Ｐ＞０． ０５）；角膜 ｈａｚｅ与切削深度两组均无显著相关关系 （ Ｐ＞０． ０５）。结论同一个体，预矫度高的一眼，ＰＲＫ术后的预测性及屈光稳定性较另一眼降低，但不显著加重角 膜ｈａｚｅ的程度；个体差异性是ＰＲＫ术后角膜ｈａｚｅ的一个重要的影响因素
Objective To study the effect of different pre-alignment on laser photorefractive keratectomy for the treatment of myopia in the same individual. Methods One hundred and sixty six eyes (272 eyes) with myopia different from each other by ≥ 2.00D were divided into low diopter group (group Ⅰ) and high diopter group (group Ⅱ). PRK postoperative follow-up 1 year of uncorrected visual acuity, residual refraction and corneal haze for statistical analysis. Results One year after PRK, the uncorrected visual acuity of group Ⅰ and group Ⅱ was 0. 69 ± 0. 33 and 0. 62 ± 0. 38, no significant difference between groups (P> 0.05); residual myopia in the pre-degree ± 0. 50D and ± 1. In group I, there were 76 eyes (55.88%) and 95 eyes (69.85%) in group Ⅰ, 45 eyes (33. 09%) and 72 eyes (52. 94%) in group Ⅱ, (P <0.01). Within ± 2.00D, 98 eyes (72.22%) in group Ⅰ and 87 eyes (63.97%) in group Ⅱ showed no significant difference (P> 0) .05). There was no significant difference in corneal haze between 1, 3, 6 and 12 months after follow-up (P> 0.05). Corneal haze had no significant correlation with depth of cut . 05). CONCLUSIONS: In the same individual, with a high degree of pre-correction, predictability and refractive stability after PRK were lower than those at the other eye but did not significantly increase the degree of corneal haze. Individual variability was an important influence on corneal haze after PRK factor