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目的探讨非霍奇金淋巴瘤(NHL)的临床特征、病理类型、治疗方法等对临床疗效及预后的影响。方法回顾分析53例NHL患者的临床资料。结果结内NHL组与结外NHL(PE-NHL)组患者在男女性别比例、平均发病年龄、临床分期、分组、病理分型、5年总生存率等方面的差异均无统计学意义(均P>0.05),但PE-NHL患者IPI评分低危组比例显著高于结内NHL(P<0.01),治疗有效率也明显高于结内NHL(P<0.05)。手术后化疗组与单纯化疗组比较,治疗有效率、5年总生存率差异均无统计学意义(均P>0.05)。结论 NHL的IPI分组能提示疗效、帮助判定预后。手术对NHL的疗效、预后无明显影响。
Objective To investigate the clinical characteristics and prognosis of non-Hodgkin’s lymphoma (NHL). Methods The clinical data of 53 patients with NHL were retrospectively analyzed. Results There was no significant difference in sex ratio, average age of onset, clinical stage, grouping, pathological type, 5-year overall survival between NHL group and NHL group P> 0.05). However, the proportion of patients with low-risk IPI score in PE-NHL group was significantly higher than that in nodal NHL group (P <0.01). The treatment efficiency was also significantly higher than that in nodal NHL group (P <0.05). Compared with the chemotherapy alone group, there was no significant difference in the 5-year overall survival rate between the two groups (P> 0.05). Conclusions The IPL grouping of NHL can suggest curative effect and help to judge the prognosis. Surgery on the efficacy of NHL, no significant prognosis.