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类风湿关节炎(RA)的发生率、致残率及死亡率均相当高,而且疗效差。目前尚缺乏 RA 远期疗效的观察。作者报道一组 RA 治疗20年的观察,以期找出影响预后的因素。研究对象为1964～1986年在 Droitwich 风湿病中心连续收治的112(男32,女80)例 RA 患者年龄在30岁以下17例,30～60岁82例,60岁以上13例。全部患者采用类固醇、金制剂和氯喹治疗,18例加用青霉胺,23例加用细胞毒药物。评价方法:①功能分级包括:Ⅰ—无症状;Ⅱ—轻度功能受限;Ⅲ—重度
Rheumatoid arthritis (RA) incidence, disability and mortality are quite high, and poor efficacy. Currently there is a lack of long-term observation of RA. The authors report a group of 20-year observation of RA treatment in order to find out the factors that affect the prognosis. The study population consisted of 112 patients (32 males, 80 females) with RA under the age of 30 years old, 82 patients aged 30-60 years, and 13 patients aged 60 years and older, who were consecutively admitted to the Droitwich Center for Rheumatology from 1964 to 1986. All patients were treated with steroids, gold preparations and chloroquine, 18 with penicillamine and 23 with cytotoxic drugs. Evaluation methods: ① functional classification include: Ⅰ-asymptomatic; Ⅱ-mild limited function; Ⅲ-severe