近年来急性酒精中毒屡有发生 ,已成为急诊常见病之一 ,至今尚无特效解毒药物 ,过去主要采用对症支持疗法 ,效果并不理想 ,近年来应用阿片受体拮抗剂———纳络酮治疗急性酒精中毒 ,发现在催醒效果、降低病死率等方面均优于常规治疗[1] ,为了探讨最佳给药方法 ,本文对三种给药方 In recent years, acute alcoholism has occurred frequently, has become one of the common emergency, there is no effective detoxification drugs, the past mainly used symptomatic and supportive therapy, the effect is not ideal, in recent years the use of opioid receptor antagonist --- naloxone Treatment of acute alcoholism, found that in the wake-up effect, reduce mortality and other aspects are superior to conventional treatment [1], in order to explore the best method of administration,