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菲诺哌啶(phenoperidin)是一种强效镇痛药,其止痛效果为吗啡的75倍,为度冷丁的270倍,具有奏效快、毒性小、使用安全等特点。上海第一医学院药学系于1981年试制该药成功。由上海中山医院麻醉科、肿瘤医院化疗科、中医科、妇科,以及华山医院内科等临床使用共206例。结果与文献报道一致,且为静吸复合全麻于体外循环心脏直视手术开辟了新的途径。其镇痛作用可持续8h以上,菲诺哌啶对晚期癌症患者也有显著的镇痛效果,一般4～5min生效,维持4～48h,即使对强痛定或度冷丁已无疗效的患者也能奏效。偶有轻度头昏、呕吐,但无其它不良反应,故深受患者欢迎。
Phenoperidin (phenoperidin) is a potent analgesic with analgesic effects of 75 times that of morphine and 270 times of meperidine. It is characterized by rapid response, low toxicity and safe use. Shanghai First Medical College Pharmacy trial in 1981 the success of the drug. A total of 206 cases were used clinically in Department of Anesthesiology, Cancer Hospital of Shanghai Cancer Hospital, Department of Traditional Chinese Medicine, Gynecology, and Huashan Hospital. The results reported in the literature, and for static combined with general anesthesia in open heart surgery open a new way. Its analgesic effect can be sustained over 8h, and phenforpide also has a significant analgesic effect on patients with advanced cancer. It usually takes 4 to 5 minutes to effect for 4 to 48 hours even if it is not effective for patients with strong pain or with meperidine Effective. Occasionally mild dizziness, vomiting, but no other adverse reactions, it welcomed by patients.