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目的:为探讨淋巴管内注入抗癌药物治疗恶性淋巴瘤的临床价值。方法:通过观察10例淋巴瘤病人淋巴管内注入131I-博来霉素的药时曲线变化。结果:①淋巴管内注入抗癌药物,注药侧淋巴链中淋巴瘤组织内示踪物浓度高、持续时间长。②非注药侧淋巴链中淋巴瘤组织内示踪物浓度峰值虽与静脉注药相同,血中示踪物高峰浓度虽低于静脉给药,但它们较高的示踪物浓度持续时间明显延长。结论:提示该方法可能是一种治疗恶性淋巴瘤的有效的方法。
Objective: To explore the clinical value of lymphatic injection of anti-cancer drugs for malignant lymphoma. METHODS: The curve of 131I-Bleomycin in the lymphatics of 10 patients with lymphoma was observed. RESULTS: 1 The anti-cancer drugs were injected into the lymphatic vessels. The concentration of tracer in the lymphoma tissues in the lymph nodes was high and the duration was long. 2 Although the peak concentration of tracer in non-injection side lymph node tissues is the same as that of intravenous injection, the peak concentration of tracer in blood is lower than that of intravenous administration, but their higher tracer concentration duration is prolonged. . Conclusion: It is suggested that this method may be an effective method for the treatment of malignant lymphoma.