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本研究用流式细胞仪测定了正常人及系统性红斑狼疮（ＳＬＥ）病人外周血１７种单克隆抗体标记Ｔ、Ｂ淋巴细胞百分数的变化。结果显示ＳＬＥ活动期病人Ｔ８及２Ｈ４细胞均低于正常，４８４细胞则高于正常，其他标记Ｔ细胞亦有不同程度的增减，提示免疫调节Ｔ细胞，特别是Ｔ４细胞中的２Ｈ４亚群的异常，是ＳＬＥ病人免疫调节异常及疾病活动的关键所在。
In this study, flow cytometry was used to measure the percentage of T and B lymphocytes of 17 kinds of monoclonal antibodies in peripheral blood of normal people and patients with systemic lupus erythematosus (SLE). The results showed that T8 and 2H4 cells in patients with active SLE were lower than normal, 484 cells were higher than normal, and other markers of T cells also increased and decreased to varying degrees, suggesting that immunoregulatory T cells, especially T4 cells 2H4 subpopulation Abnormal, is the key to immune dysfunction and disease activity in SLE patients.