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目的:观察中药调周法结合西药治疗卵巢早衰的临床疗效。方法:将48例卵巢早衰患者随机分为2组,对照组24例口服避孕药妈富隆片,治疗组24例在对照组治疗的基础上加用中药调周法,并进行疗效评估,测定血清FSH、LH、E2水平,并对月经来潮及潮热汗出等症状改善情况进行比较。结果:治疗后随访6个月,两组总有效率分别为87.5%及62.5%,且治疗组疗效更佳(P<0.05);两组均能改善血清FSH、LH、E2水平,治疗前后相比差异均具有统计学意义(P<0.01),但治疗后两组间的三种血清水平差异无统计学意义(P>0.1);治疗组更能改善月经来潮及潮热汗出情况,与对照组相比较,差异有统计学意义(P<0.05)。结论:中药调周法结合西药对卵巢早衰有较好的临床疗效,并能改善月经来潮及潮热盗汗症状。
Objective: To observe the clinical efficacy of traditional Chinese medicine combined with western medicine in the treatment of premature ovarian failure. Methods: Forty-eight patients with premature ovarian failure were randomly divided into two groups. Control group, 24 cases of oral contraceptives mother-Fulong tablets, the treatment group 24 cases in the control group based on the treatment with traditional Chinese medicine adjusting the week method, and efficacy evaluation, serum FSH, LH, E2 levels, and menstrual cramps and hot flashes sweating and other symptoms were compared. Results: After 6 months of follow-up, the total effective rates of the two groups were 87.5% and 62.5%, respectively, and the treatment group had better effect (P <0.05); both groups could improve the levels of serum FSH, LH and E2, (P <0.01). However, there was no significant difference in the three serum levels between the two groups after treatment (P> 0.1). The treatment group was better able to improve the menstrual cramps and hot flashes, and the difference was statistically significant Compared with the control group, the difference was statistically significant (P <0.05). Conclusion: The combination of traditional Chinese medicine and western medicine has a good clinical effect on premature ovarian failure, and can improve menstrual cramps and hot flashes sweating symptoms.