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目的观察1 ,6 二磷酸果糖治疗小儿急性偏瘫的临床疗效。方法在常规综合治疗基础上对42例小儿急性偏瘫患儿采用1,6 二磷酸果糖治疗 ,并观察疗效 ,同时与36例常规综合治疗组患儿进行比较。结果治疗组颅内高压征较对照组明显改善(治疗组2 3±0 46天 ,对照组3 92±0 60天 ,P0 01)。两组病人瘫痪完全恢复时间有明显差异(治疗组9 24±0 24天 ,对照组13 84±0 86天 ,P0 01)。结论1,6 二磷酸果糖对急性期的脑瘫治疗及脑功能恢复确有疗效。
Objective To observe the clinical efficacy of 1, 6 fructose diphosphate in the treatment of pediatric acute hemiplegia. Methods Forty-two children with acute hemiplegia were treated with fructose-1,6 diphosphate (PBS) on the basis of routine comprehensive treatment and the curative effect was observed. At the same time, 36 children with conventional combined therapy were also compared. Results The intracranial hypertension in the treatment group was significantly improved compared with the control group (23 ± 46 days in the treatment group and 392 ± 60 days in the control group, P0 01). There was a significant difference in the complete recovery time between two groups of patients (9 24 ± 0 24 days in the treatment group and 13 84 ± 0 86 days in the control group, P0 01). Conclusion Fructose 1, 6 diphosphate has therapeutic effect on cerebral palsy and brain function recovery in acute phase.