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目的:探讨纳洛酮联合血塞通治疗老年急性脑梗死的临床疗效。方法:将96例老年急性脑梗死患者随机分为两组,治疗组48例给予纳洛酮联合血塞通治疗,对照组48例给予复方丹参和川芎嗪治疗。观察比较两组的临床疗效。结果:治疗组总有效率为95.8%,对照组总有效率为87.5%,治疗组的疗效优于对照组,两组比较差异有统计学意义(P<0.05)。治疗组神经缺损评分、血浆黏度、红细胞压积参数改善程度优于对照组。治疗组和对照组不良反应发生率分别为18.8%和37.5%,两组比较差异有统计学意义(P<0.05)。结论:纳洛酮联合血塞通治疗老年急性脑梗死的疗效确切,不良反应发生较少,值得临床推广。
Objective: To investigate the clinical effect of naloxone combined with Xuesaitong in the treatment of senile acute cerebral infarction. Methods: Ninety-six elderly patients with acute cerebral infarction were randomly divided into two groups. The treatment group was treated with naloxone and Xuesaitong, and the control group with 48 cases treated with salvia miltiorrhiza and ligustrazine. Observed and compared the clinical efficacy of the two groups. Results: The total effective rate was 95.8% in the treatment group and 87.5% in the control group. The curative effect of the treatment group was better than that of the control group. The difference between the two groups was statistically significant (P <0.05). Neurological deficit score, plasma viscosity and hematocrit parameters in the treatment group were better than those in the control group. Adverse reactions in treatment group and control group were 18.8% and 37.5%, respectively, with significant difference between the two groups (P <0.05). Conclusion: Naloxone combined with Xuesaitong in the treatment of acute cerebral infarction in elderly patients has definite effect and few adverse reactions, which is worthy of clinical promotion.