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多发性硬化是一种较常见的中枢神经系统脱髓鞘疾病 ,T细胞介导免疫在其发病机制中起一定作用。该病的免疫耐受治疗是目前的研究热点之一 ,本文综述了近几年在其动物模型实验性自身免疫性脑脊髓炎中进行的研究工作的某些方法和进展。
Multiple sclerosis is a more common demyelinating disease of the central nervous system and T cell-mediated immunity plays a role in its pathogenesis. The immune tolerance of the disease is one of the current research hot spots, this article reviews some recent advances in animal models of experimental autoimmune encephalomyelitis.