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目的 探讨乳腺癌的转移规律，评价临床分期及病理类型与骨转移的关系。方法 对９６ 例乳腺癌术后患者进行了放射性核素全身骨显像。结果 骨转移５５ 例，其中多发性骨转移４４ 例，骨转移的部位以肋骨为多见，其次是脊柱、骨盆。Ⅰ～Ⅳ期乳腺癌的骨转移率，分别是１３ ．３ ％ 、５０％ 、６５．２ ％ 和９４．４ ％ 。在浸润性非特殊型乳腺癌中，髓样癌、单纯癌、腺癌、浸润性导管癌及浸润性小叶癌骨转移的发生率，分别为８５．７％ 、６６ ．７ ％ 、５４．５ ％ 、３９ ．３ ％ 、３３ ．３ ％ 。结论 Ⅰ～Ⅳ期乳腺癌的骨转移的发生率呈明显增高趋势；常见的单纯癌骨转移率高于浸润性导管癌。
Objective To investigate the rule of breast cancer metastasis, evaluate the relationship between clinical stage and pathological type and bone metastasis. Methods 96 cases of postoperative breast cancer patients underwent radionuclide whole body bone imaging. Results 55 cases of bone metastases, of which 44 cases of multiple bone metastases, the site of bone metastasis is more common ribs, followed by the spine, pelvis. The bone metastases of stage Ⅰ-Ⅳ breast cancer were 13. 3%, 50%, 65.2% and 94.4%. In invasive non-specific breast cancer, the incidence of bone metastases of medullary carcinoma, simple carcinoma, adenocarcinoma, invasive ductal carcinoma and invasive lobular carcinoma were 85.7% and 66 respectively. 7%, 54.5%, 39. 3%, 33. 3%. Conclusions The incidence of bone metastasis in stage Ⅰ ~ Ⅳ breast cancer is obviously increased. The rate of bone metastasis in simple carcinoma is higher than that in invasive ductal carcinoma.