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硝唑咪是目前治疗血吸虫病的首选药物,治疗人数已达20万以上。该药有杀虫作用,近来又发现对小白鼠的迟发型超敏感性有强大而且是长效的抑制作用。剂量小至只有治疗血吸虫病每日剂量的百分之一的单剂硝唑咪对曼氏血吸虫卵周围的肉芽肿形成和溶解性血吸虫卵抗原引起的迟发性脚垫水肿都有明显抑制作用。比治疗所用的剂量小得多的硝唑咪对小白鼠同种异体植物的排斥也有明显的减速作用。
Nitazoxanide is the drug of choice for the treatment of schistosomiasis, the treatment of the number has reached more than 200,000. The drug has a pesticidal effect, and recently found that the late-type hypersensitivity mice have a strong and long-lasting inhibition. A single dose of nimodipine alone at a dose as small as one percent of the daily dose for treating schistosomiasis significantly inhibits the formation of granulomas around Schistosoma mansoni eggs and the delayed footpad edema caused by lysogenic egg antigen of the schistosome . The small dose of nitazoxan compared with the treatment of mice with allograft rejection has obvious decelerating effect.