肾上腺素所致肺水肿类似中枢性肺水肿,具有动力性及非动力性双重机制。此时,动脉血中PaO_2、O_2Sat明显下降、PaCO_2明显上升,pH下降,红细胞超氧化物歧化酶含量下降,654-2与川芎嚓能防止上述异常变化,并使之趋于正常。实验显示了654-2及川芎嗪对肺水肿防止作用的部分机理。 Epinephrine-induced pulmonary edema is similar to central pulmonary edema, and has a dual mechanism of dynamic and non-dynamic. At this point, arterial blood PaO 2 , O 2 Sat decreased significantly, PaCO 2 increased significantly, pH decreased, red cell superoxide dismutase content decreased, 654-2 and Chuanxiong can prevent the above abnormal changes, and make it normal. Experiments have shown some of the mechanisms of 654-2 and tetramethylpyrazine in preventing pulmonary edema.