许多研究发现蛋白质高度乙酰化与葡萄糖不耐受和胰岛素抵抗之间具有一定关联性,这表明调节乙酰化修饰组的酶可能在糖代谢的病理学过程中发挥重要作用。近日,来自美国的科学家在国际学术期刊diabetes在线发表了一项最新科研进展,他们发现去乙酰化酶sirt3在促进机体对葡萄糖的处理,增强线粒体功能,改善饮食诱导的胰岛素抵抗方面具有重要作用。 Numerous studies have found that there is a correlation between high protein acetylation and glucose intolerance and insulin resistance, suggesting that enzymes that regulate the acetylation group may play an important role in the pathophysiology of glucose metabolism. Recently, scientists from the United States published an online research report in the international journal Diabetes. They found that sirt3 plays an important role in promoting the body’s ability to process glucose, enhancing mitochondrial function and improving diet-induced insulin resistance.