论文部分内容阅读
The combination of herbs and drugs is one of the most important approaches in the prevention and treatment of diseases in the integrated traditional and Western medicine(ITWM).While most medical practices have proved that the combination of herbs and drugs led to a clinical efficacy that was often superior to merely using only one of them;results from some studies have triggered adverse reactions to such an approach.Since few herb-drug interaction studies were carried out during treatments combining herbs and drugs,it really restricts the development of treatment and treatment theory of the combination of herbs and drugs.Given that herb-drug interactions may occur through the main pathway of cytochrome P450 enzymes and transporters;then to exhaustively study the role and impact of herbs in drug metabolism,as well as to establish a corresponding database,is of great significance for guiding the rational combination of herbs and drugs.When the herb-drug interaction information platform is implemented,we would get at ease a reasonable herb-drug prescription to achieve a better outcome,reduce dosage of some expensive drugs preserving the same efficacy,or even reduce some side effects of particular drugs;which might also promote the dynamic combination of Chinese and Western medicine,and accelerate the theory development of ITWM.
The combination of herbs and drugs is one of the most important approaches in the prevention and treatment of diseases in the integrated traditional and Western medicine (ITWM) .While most medical practices have proven that the combination of herbs and drugs led to a clinical efficacy that because often superior to merely using only one of them; results from some studies have unsupported reactions to such an an approach theory of the combination of herbs and drugs. Given that herb-drug interactions may occur through the main pathway of cytochrome P450 enzymes and transporters; then to exhaustively study the role and impact of herbs in drug metabolism, as well as to establish a corresponding database , is of great significance for guiding the rational combination of herbs and drugs. When the herb-drug interaction information platform i s implemented, we would get at ease a reasonable herb-drug prescription to achieve a better outcome, reduce dosage of some expensive drugs preserving the same efficacy, or even reduce some side effects of of drugs; which might also promote the dynamic combination of Chinese and Western medicine, and accelerate the theory development of ITWM.