为研究甘露醇导致肾功能损害的影响因素,本文收集1996年神经外科住院病例250例,利用协力医学软件和SPSS/PC+软件建立数据库,进行描述性分析及单因素和Lo-gistic回归分析。结果表明:男性、高龄、脑出血和脑外伤、冬季和春季、原已存在潜在肾功能损害因素(如肾脏病、糖尿病、高血压等)、愈后不良患者等,在使用甘露醇治疗时,肾功能损害的发生率明显升高。本文并就统计结果进行了分析和讨论。 In order to study the influencing factors of mannitol-induced renal dysfunction, we collected 250 inpatients with neurosurgery in 1996. Data were collected using medical software and SPSS / PC + software. Descriptive analysis, single-factor and Lo-gistic regression analysis were performed. The results showed that: men, elderly, cerebral hemorrhage and traumatic brain injury in winter and spring, the original existence of potential renal damage factors (such as kidney disease, diabetes, hypertension, etc.), the worse after the patient, the use of mannitol treatment, The incidence of renal dysfunction was significantly increased. This article also analyzes and discusses the statistical results.