论文部分内容阅读
目的探讨术前介入性动脉栓塞化疗(TACE)在不可切除型肝母细胞瘤治疗中的可行性。方法分析对8例经检查诊断为不可切除型肝母细胞瘤行TACE的治疗结果。结果8例患儿TACE后均有不同程度呕吐、发热、一过性肝功能损害,1例有骨髓抑制,无心、肾功能损害。有6例复查B超检查,肿瘤体积较前均有明显缩小,缩小比例为22.5%~57.5%;5例手术完整切除,均已无瘤存活1~4年,3例复诊检查发现有肺转移或多发转移,家属放弃进一步治疗后死亡。结论TACE具有化疗药物剂量小、全身副作用少、化疗效果好的优点,可作为一种术前治疗方法应用于不可切除型肝母细胞瘤。
Objective To investigate the feasibility of preoperative interventional arterial chemoembolization (TACE) in the treatment of unresectable hepatoblastoma. Methods TACE results of 8 patients with undiagnosed hepatoblastoma diagnosed by examination were analyzed. Results After TACE, 8 patients had different degrees of vomiting, fever, transient liver function damage, 1 case had bone marrow suppression, no heart and kidney damage. There were 6 cases of B-ultrasound examination, the tumor volume was significantly reduced compared with the previous, the proportion of reduction was 22.5% to 57.5%; 5 cases of complete surgical resection, have been tumor-free survival for 1 to 4 years, 3 cases of return examination found that there is lung metastasis With multiple transfers, family members die after further treatment. Conclusions TACE has the advantages of small dosage of chemotherapy drugs, less systemic side effects, and good chemotherapy effect. It can be used as a preoperative treatment method for unresectable hepatoblastoma.