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目的了解北京市石景山区健康人群脊髓灰质炎(简称脊灰)抗体水平,为制定各项卫生防病措施提供科学依据。方法采用随机抽样方法,对石景山区244名健康人群进行血标本采集,使用酶联免疫吸附试验检测脊灰中和抗体。结果Ⅰ、Ⅱ、Ⅲ型中和抗体阳性率分别为96.72%、95.90%和95.90%;几何平均滴度(GMT)分别为1∶84.06、1∶70.10和1∶57.12。不同性别、年龄、免疫史间抗体水平差异有统计学意义。不同户籍间抗体水平差异无统计学意义。结论石景山区健康人群脊灰抗体阳性率普遍较高,形成了有效的免疫屏障。
Objective To understand the level of poliomyelitis antibody in healthy people in Shijingshan District, Beijing, and to provide a scientific basis for the development of various health and disease prevention measures. Methods Blood samples were collected from 244 healthy people in Shijingshan District by random sampling method and the neutralizing antibodies of polio were detected by enzyme linked immunosorbent assay. Results The positive rates of neutralizing antibodies of type Ⅰ, Ⅱ and Ⅲ were 96.72%, 95.90% and 95.90% respectively. The geometric mean titers (GMT) were 1:84.06,1:70.10 and 1:57.12 respectively. There were significant differences in antibody levels between different gender, age and immunization history. There was no significant difference in antibody levels between different household registrations. Conclusion The positive rate of poliovirus in healthy population in Shijingshan District is generally high, forming an effective immune barrier.