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在对泽泻(Alisima orientale)生物活性成分的研究过程中,发现两种新三萜成分具有血管舒张怍用,并进行了分离和鉴定。将泽泻根茎的甲醇提取物置于乙酸乙酯-水混合溶剂中,乙酸乙酯可溶性部分经普通和逆相硅胶柱层析及HPLC层析,得alismalactone23-乙酸酯(1,0.0031%)、alismaketones-A23-乙酸酯(2,0.0022%)、-B 23-乙酸酯(0.0019%)、-C乙酸酯(0.0014%)、-D 23-乙酸酯(0.0010%)、-E 23-乙酸酯(0.0010%)、-F 23-乙酸酯(0.0012%)、-G
During the study of the bioactive components of Alisima orientale, two new triterpenoids were found to have vasodilatory properties and were isolated and identified. The methanol extract of Rhizoma Rhizoma Rhizome Rhizome was placed in ethyl acetate-water mixed solvent, and the soluble part of ethyl acetate was subjected to normal and reverse phase silica gel column chromatography and HPLC chromatography to obtain alismalactone23-acetate (1,0.0031%). alismaketones-A23-acetate (2,0.0022%), -B 23-acetate (0.0019%), -C acetate (0.0014%), -D 23-acetate (0.0010%), -E 23-Acetate (0.0010%), -F 23-Acetate (0.0012%), -G