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选用断奶雄性大鼠,分为三组,每组30只。第一组饮水中含硒酸钠浓度为24毫克/升,以产生肝硬变;第二组接触160毫克/升的四氯化碳蒸气,每天5分钟,每周5天,以产生弥漫性肝纤维化;第三组为对照。6周后测定动物血浆中葡萄糖-6-磷酸酶(G-6-P)、谷丙转氨酶(GPT)和胆碱酯酶活性,胆红素浓度,蛋白质成分,胶体红絮状试验,硫酸锌浊度和尿粪卟啉、尿胆素原以及进行磺溴酞(BSP)和马尿酸试验,并将每组大鼠各处死6只,称
Weaning male rats were divided into three groups of 30 rats. The first group contained 24 mg / L sodium selenate in the drinking water to produce cirrhosis; the second group was exposed to 160 mg / L of carbon tetrachloride vapor for 5 minutes daily for 5 days a week to produce diffuse Liver fibrosis; the third group as a control. After 6 weeks, the activities of glucose-6-phosphatase (G-6-P), alanine aminotransferase (GPT) and cholinesterase, bilirubin concentration, protein composition, colloidal red flocculent test, zinc sulfate Turbidity and urinary coproporphyrin, urobilinogen and sulfur bromophthalide (BSP) and hippuric acid test, and each group of rats were sacrificed 6, said