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红霉素片是一种常用的大环内脂类抗生素。目前测定其溶出度的常用方法有三种:占吨氢醇法、硫酸显色法—中国药典95版方法、氢氧化钠法—美国药典23版方法。现将以上三种定量测定方法进行比较,供药检工作参考。 1.仪器与试剂 TU-1221紫外分光光度仪、水浴箱
Erythromycin tablets is a commonly used macrolide antibiotics. At present, there are three common methods to determine the dissolution rate: tartanol method, sulfuric acid colorimetric method - Chinese Pharmacopoeia 95th Edition method, sodium hydroxide method - the United States Pharmacopoeia 23th Edition method. Now more than three quantitative determination of methods for drug testing for reference. 1. Instruments and reagents TU-1221 UV spectrophotometer, water bath