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国外已有资料表明乙型肝炎病毒(HBV)对医护人员可造成职业性危害。为了解我省医院医源性污染对医护人员的危害情况,1986年我们对无乙肝疫苗接种史的653名职工进行HBV 感染指标(HBsAg、抗-HBs、抗-HBc)的检测,并对HBsAg、抗-HBs 及抗-HBc 皆阴性的206名职工进行了动态观察。现将结果报告如下。内容和方法填写个案调查表。每次采血5ml,分离血清在-20℃保存待检。RIA 试剂由北京生化免疫试剂中心及卫生部北京生物制品所提供。判定标准:HBsAg、抗-HBs P/N值≥10.0,抗HBc≥2.0为阳性。阳性者与前次血清参照复检,两次结果一致定为阳转。ALT≥4.0单位为异常,TTT≥7单位为异常。结果该医院共有791名职工,本次观察653名,观察率达82.5%。既往患肝炎者共60名,现患肝炎30名。肝炎的既往及现患病人HBsAg 的阳性率分别为16.7%(10/60)和
Foreign data show that hepatitis B virus (HBV) can cause occupational hazards to health care workers. In 1986, we investigated the HBV infection (HBsAg, anti-HBs, anti-HBc) in 653 workers without a history of hepatitis B vaccination in 1986 and analyzed the effects of HBsAg , 206 anti-HBs and anti-HBc-negative workers were observed. The results reported below. Content and methods Fill in the case questionnaire. Each time blood 5ml, the sera were stored at -20 ℃ to be seized. RIA reagents from Beijing Center for Biochemical Immunology and Ministry of Health, Beijing Biological Products provided. Criteria: HBsAg, anti-HBs P / N value ≥ 10.0, anti-HBc ≥ 2.0 was positive. Positive and re-examination of the reference to the previous serum, the two results agreed as a positive rotation. ALT≥4.0 unit is abnormal, TTT≥7 unit is abnormal. Results The hospital has a total of 791 employees, this observation of 653, the observation rate of 82.5%. A total of 60 former patients with hepatitis, 30 are suffering from hepatitis. The positive rates of HBsAg in past and current patients with hepatitis were 16.7% (10/60) and