Lispro胰岛素是一种合成的胰岛素类似物，已由美国FDA批准上市。Lispro是由大肠杆菌通过重组DNA方法制成的。Lispro不同于人胰岛素之处在于它将后者p链上第28和29位上的赖氨酸和脯氨酸由原来的位置颠倒过来。这种新药与未经改变的胰岛素具有类似的生物效应，且在皮下注射后吸收 Lispro insulin is a synthetic insulin analog that has been approved by the FDA for marketing. Lispro is made by E. coli by recombinant DNA methods. Lispro differs from human insulin in that it inverts the lysine and proline at positions 28 and 29 of the latter p chain from their original position. This new drug has a similar biological effect to unaltered insulin and is absorbed after subcutaneous injection